Effects of Mechanical Compression on Chondrogenesis of Human Synovium-Derived Mesenchymal Stem Cells in Agarose Hydrogel

• Matthew Phillips

Mechanical compression is a double-edged sword for cartilage transforming, and the impact of mechanical compression on chondrogenic differentiation nonetheless stays elusive so far. Herein, we examine the impact of mechanical dynamic compression on the chondrogenic differentiation of human synovium-derived mesenchymal stem cells (SMSCs). To this goal, SMSCs encapsulated in agarose hydrogels had been cultured in…