
2 Apb 4-Hne Antibody Arf1 Antibody azide azide free Cytokine Array Mouse Donkey E coli Elisa Array Influenza Kd Antibody Kdel Antibody Llama Mettl3 Antibody Mink Mouse Orangutan What Are Feeder Cells
Fabrication of Flexible pH-Responsive Agarose/Succinoglycan Hydrogels for Controlled Drug Release
Agarose/succinoglycan hydrogels have been ready as pH-responsive drug supply techniques with considerably improved flexibility, thermostability, and porosity in comparison with agarose gels alone. Agarose/succinoglycan hydrogels have been made utilizing agarose and succinoglycan, a polysaccharide straight remoted from Sinorhizobium meliloti. Mechanical and bodily properties of agarose/succinoglycan hydrogels have been investigated utilizing varied instrumental strategies similar to rheological measurements, attenuated whole reflection-Fourier rework infrared (ATR-FTIR) spectroscopic evaluation, X-ray diffraction (XRD), and field-emission scanning electron microscopy (FE-SEM).
The outcomes confirmed that the agarose/succinoglycan hydrogels turned versatile and steady community gels with an improved swelling sample in primary answer in comparison with the arduous and brittle agarose gel alone. As well as, these hydrogels confirmed a pH-responsive supply of ciprofloxacin (CPFX), with a cumulative launch of ~41% inside 35 h at pH 1.2 and full launch at pH 7.4. Agarose/succinoglycan hydrogels additionally proved to be non-toxic because of the cell cytotoxicity take a look at, suggesting that these hydrogels could be a possible pure biomaterial for biomedical functions similar to varied drug supply system and cell tradition scaffolds.
1.eight V Aqueous Symmetric Carbon-Based mostly Supercapacitors with Agarose-Certain Activated Carbons in an Acidic Electrolyte
The precise vitality of an aqueous carbon supercapacitor is mostly small, ensuing primarily from a slender potential window of aqueous electrolytes. Right here, we launched agarose, an ecologically appropriate polymer, as a novel binder to manufacture an activated carbon supercapacitor, enabling a wider potential window attributed to a excessive overpotential of the hydrogen-evolution response (HER) of agarose-bound activated carbons in sulfuric acid.
Assembled symmetric aqueous cells could be galvanostatically cycled as much as 1.eight V, attaining an enhanced vitality density of 13.5 W h/kg (9.5 µW h/cm2) at 450 W/kg (315 µW/cm2). Moreover, an amazing biking habits was obtained, with a 94.2% retention of capacitance after 10,000 cycles at 2 A/g. This work would possibly information the design of another materials for high-energy aqueous supercapacitors.
Sort 1 diabetic sufferers with extreme hypoglycemia unawareness have benefitted from mobile therapies, similar to pancreas or islet transplantation; nevertheless, donor scarcity and the necessity for immunosuppression limits widespread medical software. We beforehand developed an intravascular bioartificial pancreas (iBAP) utilizing silicon nanopore membranes (SNM) for immunoprotection.
To make sure ample nutrient supply, the iBAP will want a cell scaffold with excessive hydraulic permeability to supply mechanical assist and preserve islet viability and performance. Right here, we study the feasibility of superporous agarose (SPA) as a possible cell scaffold within the iBAP. SPA reveals 66-fold larger hydraulic permeability than the SNM together with a brief (<10 μm) diffusion distance to the closest islet.
SPA additionally helps short-term performance of each encapsulated human islets and stem-cell-derived enriched β-clusters in a convection-based system, demonstrated by excessive viability (>95%) and biphasic insulin responses to dynamic glucose stimulus. These findings recommend that the SPA scaffold won’t restrict nutrient supply in a convection-based bioartificial pancreas and deserves continued investigation.
Hepatotoxicity of copper sulfide nanoparticles in direction of hepatocyte spheroids utilizing a novel multi-concave agarose chip methodology
Goal: To discover the hepatotoxicity of copper sulfide nanoparticles (CuSNPs) towards hepatocyte spheroids.
Supplies & strategies: Aside from the normal agarose methodology to generate hepatocyte spheroids, we developed a multi-concave agarose chip (MCAC) methodology to research adjustments in hepatocyte viability, morphology, mitochondrial membrane potential, reactive oxygen species and hepatobiliary transporter by CuSNPs.
Outcomes: The MCAC methodology allowed a lot of spheroids to be obtained per pattern. CuSNPs confirmed hepatotoxicity in vitro via a lower in spheroid viability, albumin/urea manufacturing and glycogen deposition. CuSNPs additionally launched hepatocyte spheroid damage via alteration of mitochondrial membrane potential and reactive oxygen species, that might be reversed by N-acetyl-l-cysteine. CuSNPs considerably decreased the exercise of BSEP transporter by downregulating its mRNA and protein ranges. Exercise of the MRP2 transporter remained unchanged.
Conclusion: We noticed the hepatotoxicity of CuSNPs in vitro with related mechanisms in a sophisticated 3D tradition system.
A Novel Technique to Coat Dopamine-Functionalized Titanium Surfaces With Agarose-Based mostly Hydrogels for the Managed Launch of Gentamicin
Introduction: Using spinal implants for the remedy of again issues is basically affected by the insurgence of infections on the implantation web site. Antibacterial coatings have been proposed as a viable answer to restrict such infections. Nevertheless, regardless of being efficient at short-term, standard coatings lack the power to forestall infections at medium and long-term. Hydrogel-based drug supply techniques could symbolize an answer controlling the discharge of the loaded antibacterial brokers whereas bettering cell integration. Agarose, specifically, is a biocompatible pure polysaccharide identified to enhance cell development and already utilized in drug supply system formulations. On this examine, an agarose hydrogel-based coating has been developed for the managed launch of gentamicin (GS).
Strategies: Sand blasted Ti6Al4V discs have been grafted with dopamine (DOPA) answer. After, GS-loaded agarose hydrogels have been produced and additioned with tannic acid (TA) and calcium chloride (CaCl2) as crosslinkers. The totally different GS-loaded hydrogel formulations have been deposited on Ti6Al4V-DOPA surfaces, and allowed to react below UV irradiation. Floor topography, wettability and composition have been analyzed with profilometry, static contact angle measurement, XPS and FTIR spectroscopy analyses. GS launch was carried out below pseudo-physiological circumstances as much as 28 days and the launched GS was quantified utilizing a selected ELISA take a look at. The cytotoxicity of the produced coatings towards human cells have been examined, together with their antibacterial exercise towards S. aureus micro organism.
Outcomes: A homogeneous coating was obtained with all of the hydrogel formulations. Furthermore, the coatings introduced a hydrophilic habits and micro-scale floor roughness. The addition of TA within the hydrogel formulations confirmed a rise within the launch time in comparison with the traditional GS-agarose hydrogels. Furthermore, the GS launched from these gels was capable of considerably inhibit S. aureus development in comparison with the GS-agarose hydrogels. The addition of CaCl2 to the gel formulation was capable of considerably lower cytotoxicity of the TA-modified hydrogels.
Conclusions: As a consequence of their floor properties, low cytotoxicity and excessive antibacterial results, the hereby proposed gentamicin-loaded agarose-hydrogels present new perception, and symbolize a promising method for the floor modification of spinal implants, enormously impacting their software within the orthopedic surgical situation.

Enhancement of emulsion penetration in agarose gel mannequin utilizing versatile plasma remedy
Transdermal supply via the pores and skin is a gorgeous various to injection as a result of it’s potential to launch a drug with much less ache. We ready a versatile plasma patch (FPP) utilizing printed electronics methods and examined transdermal supply enhancement of a water emulsion in agarose gel in anin vitrotissue mannequin.
At room temperature, the FPP generated chilly air plasma, which provided reactive oxygen species similar to ozone on the floor of the agarose gel. The FPP remedy was efficient in enhancing the water emulsion transport into the agarose gel. The penetration depth of the emulsion within the non-plasma-treated 3% agarose gel mannequin was roughly 0.69 mm whereas that of the plasma-treated mannequin was roughly 1.21 mm.
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abx090807-500ml | Abbexa | 500 ml | EUR 460.8 |
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2117-1000 | Biovision | EUR 254.4 |
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2117-200 | Biovision | EUR 150 |
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2128-1000 | Biovision | EUR 274.8 |
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2128-200 | Biovision | EUR 164.4 |
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AR0143 | BosterBio | 200mL/pack | EUR 78 |
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KF17337 | Neuromics | 500 ml | EUR 277.2 |
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KF17339 | Neuromics | 500 ml | EUR 292.8 |
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X109-250ML | Arbor Assays | 250ML | EUR 430.8 |
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X109-25ML | Arbor Assays | 25ML | EUR 146.4 |
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BT10 | Biotix | 10 trays of 96 / pack | EUR 70.8 |
Description: Low retention, Racked, Pre-Sterile, Sample Saving Surface |
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BT100 | Biotix | 10 trays of 96 / pack | EUR 70.8 |
Description: Low retention, Racked, Pre-Sterile, Sample Saving Surface |
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BT1000.96 | Biotix | 8 trays of 96 / pack | EUR 70.8 |
Description: Low retention, Racked, Pre-Sterile, Sample Saving Surface |
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BT20 | Biotix | 10 trays of 96 / pack | EUR 70.8 |
Description: Low retention, Racked, Pre-Sterile, Sample Saving Surface |
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BT200 | Biotix | 10 trays of 96 / pack | EUR 70.8 |
Description: Low retention, Racked, Pre-Sterile, Sample Saving Surface |
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BT300 | Biotix | 10 trays of 96 / pack | EUR 70.8 |
Description: Low retention, Racked, Pre-Sterile, Sample Saving Surface |
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KF17349 | Neuromics | 500 ml | EUR 292.8 |
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KF17354 | Neuromics | 500 ml | EUR 292.8 |
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DD713002 | Scientific Laboratory Supplies | PK960 | EUR 116.28 |
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ELISA-1 | Alpha Diagnostics | 1 | EUR 242.4 |
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2140-1000 | Biovision | EUR 261.6 |
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2140-200 | Biovision | EUR 144 |
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2143-1000 | Biovision | EUR 261.6 |
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2143-200 | Biovision | EUR 144 |
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23013 | Biotium | 1kit | EUR 416.4 |
Description: Minimum order quantity: 1 unit of 1kit |
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23013-T | Biotium | 1kit | EUR 150 |
Description: Minimum order quantity: 1 unit of 1kit |
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abx090811-1000ml | Abbexa | 1000 ml | EUR 627.6 |
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KF17340 | Neuromics | 3 x 100 ml | EUR 246 |
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GR103005 | Genorise Scientific | 200 mL | EUR 154.8 |
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SB0626 | Bio Basic | 1pk, 1L | EUR 100.72 |
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SD8113 | Bio Basic | 1pk, 1L | EUR 100.72 |
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W3700-010 | GenDepot | 100ml | EUR 116.4 |
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W3700-050 | GenDepot | 500ml | EUR 198 |
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W3700-100 | GenDepot | 1L | EUR 295.2 |
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BSH100-02 | Benchmark Scientific | 1 PC | EUR 164.65 |
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BSH100-05 | Benchmark Scientific | 1 PC | EUR 176.14 |
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BSH100-1213 | Benchmark Scientific | 1 PC | EUR 164.65 |
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BSH100-1232 | Benchmark Scientific | 1 PC | EUR 164.65 |
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BSH100-15 | Benchmark Scientific | 1 PC | EUR 164.65 |
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BSH100-150 | Benchmark Scientific | 1 PC | EUR 187.62 |
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BSH100-1520 | Benchmark Scientific | 1 PC | EUR 164.65 |
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BSH100-15HL | Benchmark Scientific | 1 PC | EUR 187.62 |
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BSH100-500 | Benchmark Scientific | 1 PC | EUR 124.98 |
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BSH100-5MT | Benchmark Scientific | 1 PC | EUR 187.62 |
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BSH100-CV | Benchmark Scientific | 1 PC | EUR 164.65 |
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BSW02 | Benchmark Scientific | 1 PC | EUR 182.32 |
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BSW05 | Benchmark Scientific | 1 PC | EUR 182.32 |
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BSW10 | Benchmark Scientific | 1 PC | EUR 182.32 |
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BSW13 | Benchmark Scientific | 1 PC | EUR 182.32 |
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BSW15 | Benchmark Scientific | 1 PC | EUR 182.32 |
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BSW1500 | Benchmark Scientific | 1 PC | EUR 182.32 |
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BSW1516 | Benchmark Scientific | 1 PC | EUR 219.64 |
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BSW1520 | Benchmark Scientific | 1 PC | EUR 182.32 |
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BSW50 | Benchmark Scientific | 1 PC | EUR 182.32 |
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BSW5MT | Benchmark Scientific | 1 PC | EUR 182.32 |
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BSWHEM | Benchmark Scientific | 1 PC | EUR 284.71 |
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BSWMT | Benchmark Scientific | 1 PC | EUR 233.99 |
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BSWNMR | Benchmark Scientific | 1 PC | EUR 578.08 |
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BSWPCR1 | Benchmark Scientific | 1 PC | EUR 306.72 |
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BSWPCR2 | Benchmark Scientific | 1 PC | EUR 250.26 |
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H5000-02 | Benchmark Scientific | 1 PC | EUR 348.4 |
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H5000-025 | Benchmark Scientific | 1 PC | EUR 709.62 |
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H5000-05 | Benchmark Scientific | 1 PC | EUR 348.4 |
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H5000-12 | Benchmark Scientific | 1 PC | EUR 459.06 |
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H5000-1232 | Benchmark Scientific | 1 PC | EUR 459.06 |
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H5000-15 | Benchmark Scientific | 1 PC | EUR 348.4 |
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H5000-150 | Benchmark Scientific | 1 PC | EUR 459.06 |
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H5000-20 | Benchmark Scientific | 1 PC | EUR 459.06 |
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H5000-500 | Benchmark Scientific | 1 PC | EUR 459.06 |
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H5000-CMB | Benchmark Scientific | 1 PC | EUR 348.4 |
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H5000-CU | Benchmark Scientific | 1 PC | EUR 459.06 |
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H5000-WB | Benchmark Scientific | 1 PC | EUR 5146.62 |
![]() Neptune 1000-1250ul barrier tip |
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BT1250 | Biotix | 8 trays of 96 / pack | EUR 70.8 |
Description: Extended Length, Low retention, Racked, Pre-Sterile, Sample Saving Surface |
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WAT3262 | Scientific Laboratory Supplies | EACH | EUR 451.44 |
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9068 | Chondrex | 100 ml | EUR 155.7 |
Description: ChonBlock Blocking/Sample Dilution ELISA Buffer |
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80060 | Alpha Diagnostics | 50 ml | EUR 242.4 |
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BLO5016 | Scientific Laboratory Supplies | EACH | EUR 133.38 |
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AR0182 | BosterBio | 500mL/Pack | EUR 84 |
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AR0183 | BosterBio | 500mL/Pack | EUR 84 |
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M4104-100 | Biovision | EUR 183.6 |
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M4104-500 | Biovision | EUR 430.8 |
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SF40011 | Neuromics | 10 ml | EUR 153.6 |
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5736 | Scientific Laboratory Supplies | EACH | EUR 108.3 |
![]() Corning 3D Clear Blocking Buffer - 100mL |
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5737 | Scientific Laboratory Supplies | EACH | EUR 294.12 |
![]() Block-Free ELISA Reagent |
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M4102-250 | Biovision | EUR 542.4 |
![]() Block-Free ELISA Reagent |
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M4102-50 | Biovision | EUR 176.4 |
![]() Neptune 10ul extended length barrier tip |
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BT10XLS3 | Biotix | 10 trays of 96 / pack | EUR 70.8 |
Description: Low retention, Racked, Pre-Sterile, Sample Saving Surface |
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5730 | Scientific Laboratory Supplies | EACH | EUR 864.12 |
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ACA015 | ScyTek Laboratories | 15 ml | EUR 80.4 |
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ACA125 | ScyTek Laboratories | 125 ea. | EUR 91.2 |
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ACA500 | ScyTek Laboratories | 500 ml | EUR 121.2 |
Tags: egfr antibody adcc egfr antibody approved egfr antibody calbiochem egfr antibody cell signaling egfr antibody colon cancer egfr antibody colorectal cancer egfr antibody cst egfr antibody drug egfr antibody fda egfr antibody kras mutation egfr antibody lung cancer egfr antibody moa egfr antibody nsclc egfr antibody review egfr antibody santa cruz egfr antibody sequence egfr antibody therapy egfr antibody-drug conjugate glp 1 elisa kit protease cocktail inhibitor protease cocktail inhibitor roche protease cocktail sigma purified antibody purifying antibodies qpcr plates 401334